Hyperglycemia and bladder cancer prognosis in a Finnish population-based cohort.

ABSTRACT:

Background

Diabetes might increase risk of bladder cancer (BCa) incidence and bladder cancer specific death.

Objective

To assess the potential association between diabetes and prognosis of BCa.

Design, setting and participants

Register-based cohort study included 14,638 participants with BCa diagnosed in Finland during 1995-2012. Three databases were used to obtain information on BCa, diabetes and comorbidities. Hyperglycemia was determined by blood glucose or HbA1c. The role of antidiabetic medication use was also assessed.

Outcome measurements and statistical analysis

Associations between diabetes and BCa-specific and overall mortality were evaluated using multivariable Cox regression models.

Results and limitation

During median follow-up of 4.3 years

SUBMITTER: Vuoristo L 

PROVIDER: S-EPMC12700417 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature