Same disease, different outcomes: a retrospective cohort study of COVID-19-associated AKI across Brazil's dual-tiered healthcare system.

ABSTRACT:

Introduction

Acute kidney injury (AKI) is a critical complication of COVID-19, yet disparities in outcomes between public and private healthcare systems remain underexplored. Brazil's two-tiered healthcare system offers a unique setting to evaluate how resource allocation impacts AKI outcomes. This study compares AKI epidemiology in COVID-19 patients treated in two Brazilian hospitals, one publicly governed and the other of privately governed.

Methods

This retrospective cohort study analyzed 2,333 ICU patients with RT-PCR-confirmed COVID-19 (public 1,041; private 1,292, March 2020-April 2022). AKI was defined per KDIGO criteria and recovery was classified using ADQI guidelines. Multivariate logistic regression and Cox models were used to assess predictors of AKI incidence an

SUBMITTER: Faria NP 

PROVIDER: S-EPMC12700444 | biostudies-literature | 2026 Apr-Jun

REPOSITORIES: biostudies-literature