Incidence and risk factors for chronic kidney disease in individuals with type 1 diabetes: A population-based study in Salford, Manchester.

ABSTRACT:

Aims

Chronic kidney disease (CKD) is a serious and common complication of type 1 diabetes (T1D). Despite improvements in diabetes management, the prevalence of CKD in people with T1D remains high. However, large-scale, real-world data from the UK are limited. This study aimed to provide contemporary estimates of CKD incidence and its associated risk factors in a population with T1D in Salford, Greater Manchester.

Methods

We conducted a retrospective cohort study using anonymised electronic health records from the Salford Integrated Record Research Database between 2010 and 2023. Adults with T1D were assessed for CKD, defined as an estimated glomerular filtration rate (eGFR) <60 mL/min/1.73 m² and/or albuminuria (urine albumin-to-creatinine ratio ≥3 mg/mmol), confi

SUBMITTER: Habte-Asres HH 

PROVIDER: S-EPMC12700510 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature