Adaptive Hemodiafiltration Strategies in a Full-Term Pregnancy with End-Stage Kidney Disease: A Case Report.

ABSTRACT:

Introduction

Managing pregnancy in patients with end-stage kidney disease (ESKD) undergoing dialysis is challenging, with hypoalbuminemia significantly increasing risks to both maternal and neonatal outcomes. Intensive hemodialysis regimens are recommended; however, individualized and adaptive dialysis strategies, such as sequential online hemodiafiltration (OL-HDF) and intermittent HDF (i-HDF), may be required to optimize care in complex cases.

Case presentation

We report the case of a 27-year-old Japanese woman with ESKD who transitioned from OL-HDF to i-HDF during pregnancy due to progressive hypoalbuminemia at 30 + 5 weeks of gestation. Dry weight adjustments were guided by human atrial natriuretic peptide (hANP) levels, blood pressure measurements, and bioimpedance anal

SUBMITTER: Sakai M 

PROVIDER: S-EPMC12700590 | biostudies-literature | 2025 Jan-Dec

REPOSITORIES: biostudies-literature