Multiorgan Dysfunction in Severe Acute Pancreatitis: A Case of Septic Shock, Renal Cortical Necrosis, and Takotsubo Cardiomyopathy.

ABSTRACT:

Introduction

Severe acute pancreatitis (AP) may evolve rapidly into systemic inflammatory response syndrome and multiorgan dysfunction syndrome, posing significant management challenges.

Case presentation

We present a rare and complex case of severe AP complicated by septic shock, bilateral renal cortical necrosis (RCN), and Takotsubo cardiomyopathy (TTC). Septic shock contributed to profound hemodynamic instability, while RCN - a rare and often fatal form of acute kidney injury - added to the severity of renal dysfunction. Concurrent TTC, likely precipitated by catecholamine surges during critical illness, led to transient myocardial dysfunction.

Conclusion

This case highlights the importance of early recognition, a multidisciplinary approach, and advanced critical c

SUBMITTER: Patel B 

PROVIDER: S-EPMC12700591 | biostudies-literature | 2025 Jan-Dec

REPOSITORIES: biostudies-literature