Dementia with Grains: A Clinical Mimic of Dementia with Lewy Bodies - Case Report.

ABSTRACT:

Introduction

Dementia characterized by the accumulation of argyrophilic grains (AGs) in neurons as sole neuropathology at autopsy is known as dementia with grains (DG). The clinical features of DG include progressive memory disturbances and behavioral changes. Recently however, cases of DG presenting with parkinsonism were also described. Here, we report the first case of DG mimicking dementia with Lewy bodies.

Case presentation

A 72-year-old male patient was seen at our outpatient memory clinic with progressive complaints in multiple cognitive domains (memory, orientation, praxis, and executive function), fluctuations in arousal and behavioral changes. In addition, he reported neuropsychiatric symptoms, including a depressed mood and visual hallucinations. During neurologic

SUBMITTER: Gardiner SL 

PROVIDER: S-EPMC12700594 | biostudies-literature | 2025 Jan-Dec

REPOSITORIES: biostudies-literature