Performance and challenges of malaria rapid diagnostic tests in endemic regions of Africa.

ABSTRACT: Rapid diagnostic tests (RDTs) have revolutionized malaria diagnosis, playing a crucial role in improving timely treatment and supporting surveillance efforts, especially in resource-limited settings. However, the performance of RDTs can vary widely due to factors such as parasite genetic diversity, environmental conditions, and operational challenges. Understanding these variations is essential to ensuring accurate and reliable malaria diagnosis. This systematic review and meta-analysis critically evaluate the diagnostic performance of malaria RDTs across sub-Saharan Africa, identifying key gaps and proposing strategies for developing novel tests. By pooling data from 48 studies, the analysis quantifies the sensitivity and specificity of various RDT brands in different settings. The result

SUBMITTER: Ojeniyi FD 

PROVIDER: S-EPMC12701009 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature