Cyanostyryl-Guanidiniocarbonyl-Pyrrole Amphiphiles: From Aggregation-Induced Emission to Photodimerization, Self-Assembly, and Bioimaging.

ABSTRACT: Two Cyanostyryl-guanidiniocarbonyl-pyrrole based amphiphiles are synthesized and examined in detail. In addition to achieving aggregation-induced emission from self-assembly, resulting in nanoparticles, it was found that the observed [2 + 2] photocycloaddition tunes the photophysical properties. The guanidiniocarbonyl-pyrrole component of these hybrid luminophores is shown to bind oxo-anions, such as pyrene-tetracarboxylate, as confirmed by fluorescence lifetime measurements. Moreover, both amphiphiles are used in bio-imaging experiments with HeLa cells, demonstrating effective cellular uptake.

SUBMITTER: Rudolph K 

PROVIDER: S-EPMC12701296 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature