Global lineages of non-tuberculous mycobacteria in residential water samples from Germany.

ABSTRACT: Non-tuberculous mycobacteria (NTM) are ubiquitous environmental organisms that can cause severe infections in vulnerable individuals. However, the environmental reservoirs and transmission routes of clinically relevant NTM remain insufficiently understood. Given the rising incidence of NTM infections, understanding where these bacteria thrive can inform public health measures and reduce infection risk. In this study, we analysed the prevalence and genetic diversity of mycobacteria in indoor water samples from private residences and a hospital in Frankfurt am Main, Germany, and characterised them using whole genome sequencing and phenotypic drug susceptibility testing. Core genome multi-locus sequence typing (cgMLST) was employed to compare environmental isolates with nearly 3,000 clinical

SUBMITTER: Diricks M 

PROVIDER: S-EPMC12701587 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature