SWI/SNF chromatin remodeling factor BRAHMA promotes de novo shoot regeneration by epigenetic priming via H3K27me3 removal.

ABSTRACT: Plants have a remarkable capacity for regeneration. Recent studies have identified associations between plant regeneration and epigenetic regulators, thereby supporting the hypothesis that dynamic gene expression changes occur during the regeneration process. Notably, the association with chromatin remodeling factors remains to be elucidated. In this study, we demonstrated that BRAHMA (BRM), a core ATPase of the BRM-associated SWI/SNF (BAS) chromatin remodeling complex, plays a crucial role in the shoot regeneration process via root-derived callus formation. Phenotypic and transcriptomic analyses demonstrated that BRM exerts a substantial effect on the transition of gene expression from callus formation to shoot regeneration. Furthermore, epigenomic analysis revealed that BRM contributes t

SUBMITTER: Horie A 

PROVIDER: S-EPMC12701749 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature