Binge drinking acutely induces hepatic steatosis which is readily reversible: A real-world observational study in healthy adults.

ABSTRACT:

Background & aims

Binge drinking is a common pattern of alcohol intake often considered particularly harmful. However, its immediate effects on the development of hepatic steatosis and early alcohol-related liver injury are not well established. This study aimed to investigate the acute effects of binge drinking on the liver and its reversibility in healthy individuals.

Methods

Healthy adults were studied in a real-world setting before, the day after, and 10 days after attending a 3-day festival. The participants were alcohol abstinent 1 week prior to the first visit and between the last two visits. Each visit included liver MRI-proton density fat fraction and elastography, and blood tests. Alcohol and food intake were self-reported during the festival, and blood alcohol con

SUBMITTER: Kjærgaard K 

PROVIDER: S-EPMC12701993 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature