Right Atrial Function is Impaired in Pediatric Pulmonary Arterial Hypertension: A Multi-center Cardiovascular Magnetic Resonance Study.

ABSTRACT:

Background

Impaired right atrial (RA) function is strongly predictive of adverse outcomes in adults with pulmonary arterial hypertension (PAH) but remains incompletely understood in pediatric PAH. In this pediatric multi-center retrospective cohort study using cardiovascular magnetic resonance imaging (CMR), we analyzed RA size and phasic function and its associations with PAH severity.

Methods

PAH and control pediatric patients from two centers who underwent CMR from 2010 to 2023 were identified. RA volumes were measured throughout the cardiac cycle using the single-plane, area-length method on a standard 4-chamber cine sequence. Total, conduit phase, and active phase stroke volume (SVi; indexed to BSA) and ejection fraction (EF) were calculated. A novel marker, the A/C rat

SUBMITTER: Miles KG 

PROVIDER: S-EPMC12702102 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature