A protocol for a randomized controlled trial of photobiomodulation for management of temporomandibular disorder pain in Adults.

ABSTRACT: Evidence-based treatments for painful temporomandibular disorders (TMD) are lacking. The most common treatments for painful TMDs, intraoral appliances and pain medication, provide suboptimal pain control, often leading to treatment-limiting adverse effects. Photobiomodulation therapy (PBM) shows substantial potential for the management of pain in people with a TMD; however, its efficacy for TMD pain reduction has not been rigorously tested. We will conduct a double-blind, randomized, placebo-controlled clinical trial of multimodal PBM for TMD pain. This single-site trial will randomize 130 participants, aged 18 years and older, with chronic painful TMD. Individuals will complete a detailed medical history to confirm eligibility criteria, followed by a clinical exam to confirm TMD case stat

SUBMITTER: Rubio S 

PROVIDER: S-EPMC12702193 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature