Disparities and trends in pulmonary embolism mortality with and without obesity: a nationwide US analysis.

ABSTRACT:

Background

Obesity increases the risk of pulmonary embolism (PE) through multiple mechanisms.

Objectives

This study examined mortality trends in patients with coexisting PE and obesity.

Methods

We analyzed the Centers for Disease Control and Prevention Wide-ranging Online Data for Epidemiologic Research database for individuals aged 25 years and older who died between 1999 and 2020 from concurrent PE and obesity. Temporal trends and age-adjusted mortality rates (AAMRs) were assessed using Joinpoint regression software. Annual percent changes (APCs), average annual percentage change differences, and 95% CIs were calculated, with statistical significance set at P < .05.

Results

From 1999 to 2020, the AAMR for PE with obesity increased from 5.1 (95% CI, 4.7

SUBMITTER: Goyal A 

PROVIDER: S-EPMC12702333 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature