First implementation of photon-counting dector computed tomography for optimizing segmentation in head-and-neck cancer radiotherapy.

ABSTRACT:

Background and purpose

Photon-counting detector computed tomography (PCD-CT) offers advancements over conventional energy-integrating detector computed tomography (EID-CT). This study is the first to investigate the use of PCD-CT for delineation purposes.

Materials and methods

Twelve patients with head-and-neck cancer were prospectively included. Delineation of clinical target volume (CTV) and organs at risk (OARs) was performed by three physicians using EID-CT (120 kVp) and PCD-CT at virtual monoenergetic levels of 140 keV and 50 keV. Segmentation accuracy was assessed and contouring-confidence was rated.

Results

The ratio of the mean computed tomography dose index (CTDI) for EID-CT/PCD-CT for all patients was 2.72. The study revealed high inter-observer agreement fo

SUBMITTER: Bertini N 

PROVIDER: S-EPMC12702377 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature