Silver diamine fluoride differentially affects dentin and hypomineralized enamel permeabilities.

ABSTRACT:

Objectives

To investigate the physicochemical effect of silver diamine fluoride (SDF) by correlating permeability with mineral density and elemental composition of hypomineralized enamel and carious dentin.

Methods

Enamel and dentin from human carious primary teeth with and without SDF treatment in-vivo, and hypomineralized enamel from permanent molars with and without SDF treatment in-vitro were scanned using micro X-ray computed tomography. Spatial maps of biometals (calcium, zinc), phosphorus, and silver were generated using X-ray fluorescence microprobe. Permeabilities were computed using Porous Microstructure Analysis software.

Results

The intrinsic permeability of SDF-treated carious dentin was 14.3 % lower than untreated sound dentin (6.39e-15 ± 3.01e-15 m² vs

SUBMITTER: Chou C 

PROVIDER: S-EPMC12702468 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature