Impact of individualized tidal volume strategies on intraoperative lung protection and inflammatory markers in laparoscopic cholecystectomy: a randomized controlled trial.

ABSTRACT:

Objective

The aim of this study is to evaluate the impact of individualized tidal volume settings, as compared to conventional settings on lung injury in patients undergoing laparoscopic cholecystectomy under mechanical ventilation.

Methods

A total of 40 patients scheduled for elective laparoscopic cholecystectomy at the Affiliated Hospital of Inner Mongolia Medical University between August 2024 and January 2025 were enrolled in this randomized study. Participants were randomly assigned using a random number table to either the control group (Group C, n = 20) or the experimental group (Group T, n = 20), based on the method of tidal volume adjustment. Group C received a conventional tidal volume of 8 mL/kg. In Group T, resting tidal volume was measured preoperatively and use

SUBMITTER: Wang X 

PROVIDER: S-EPMC12702722 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature