Investigating the pathways of medication adherence in renal transplant recipients based on the COM-B model: the parallel mediating effects of beliefs and emotion regulation efficacy.

ABSTRACT:

Background

Suboptimal medication adherence remains a major cause of allograft failure after kidney transplantation. Previous studies have focused on isolated factors rather than integrated mechanisms. Based on the COM-B model, this study investigates the mediating roles of medication beliefs and regulatory emotional self-efficacy (RESE) between medication literacy, social support, and medication adherence.

Methods

A cross-sectional survey included 351 kidney transplant recipients (KTRs) from a tertiary hospital in Changsha (April-July 2025). Participants completed a general information questionnaire, the Basel Assessment of Adherence to Immunosuppressive Medications Scale, the Chinese version of the RESE Scale, the Social Support Rating Scale, the Chinese Medication Literacy

SUBMITTER: Zhou L 

PROVIDER: S-EPMC12702757 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature