Codesigning a Neurocognitive Assessment Protocol for Hyperphagia: Perspectives From Stakeholders in Prader-Willi Syndrome.

ABSTRACT:

Background

Hyperphagia-characterized by an overwhelming drive to consume food-is a core feature of Prader-Willi syndrome (PWS) that profoundly impacts individuals and families. Objective measures of hyperphagia are urgently needed to support therapeutic development and improve clinical outcomes for individuals with PWS. Eye tracking may offer a scalable, noninvasive method for capturing attentional responses to food cues. By capturing visual attentional responses to food before and after eating, eye tracking may offer an indirect, objective method for assessing impairments in satiety that are associated with hyperphagia.

Methods

We adapted a previously developed eye-tracking task-designed to detect attentional bias to food stimuli in hungry versus satiated states-for use wit

SUBMITTER: Feighan SM 

PROVIDER: S-EPMC12703053 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature