Endoscopic or surgical gastroenterostomy for malignant gastric outlet obstruction: a randomised trial.

ABSTRACT:

Background

Although surgical gastrojejunostomy (SGJ) is the standard method for palliation of gastric outlet obstruction (GOO), an endoscopic method-endoscopic ultrasound-guided gastroenterostomy (EUS-GE)-has been proposed as a novel, less invasive approach.

Objective

We compared both methods to determine whether clinical outcomes for EUS-GE are superior to surgery.

Design

We conducted a multicentre, randomised superiority trial of patients with malignant GOO to receive either EUS-GE or SGJ. Primary endpoint was composite measure, consisting of Gastric Outlet Obstruction Scoring System (GOOSS) score of 0 or 1 at hospital discharge, need for reinterventions or supplemental nutrition, or procedure-related adverse events during 6-month follow-up or until death. Secondary

SUBMITTER: Bang JY 

PROVIDER: S-EPMC12703243 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature