Skeletal muscle relaxant for the treatment of fibromyalgia: a systematic review and meta-analysis of randomized controlled trials.

ABSTRACT:

Background/importance

Fibromyalgia is a complex chronic pain disorder that significantly impairs patient well-being. Evaluating the efficacy of muscle relaxants for treating fibromyalgia is crucial for improving patient care.

Objective

This study aimed to evaluate the analgesic efficacy of muscle relaxants in patients with fibromyalgia.

Evidence review

A comprehensive literature search was conducted using PubMed, EMBASE, Web of Science, ClinicalTrials.gov, and the Cochrane Library. The search included randomized controlled trials (RCTs) comparing skeletal muscle relaxants with placebo/active analgesics for fibromyalgia. The primary outcome was pain intensity, measured by standardized mean difference (SMD) in pain scores. The risk of bias of included RCTs was assessed

SUBMITTER: Shing CH 

PROVIDER: S-EPMC12703245 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature