Left ventricular ejection fraction and myocardial fibrosis in sudden cardiac death.

ABSTRACT:

Aims

Left ventricular ejection fraction (LVEF) remains the key determinant in the evaluation for the risk of sudden cardiac death (SCD). Myocardial fibrosis has gained increasingly more interest in the context of various myocardial diseases. We determined the spectrum of LVEF and evaluated the association between myocardial fibrosis and pre-SCD LVEF in a population-based SCD cohort.

Methods and results

The Fingesture study and clinical data have been collected from consecutive autopsy-verified SCD victims from Northern Finland between 1998 and 2017 (n = 5869). The cause of death was verified in medicolegal autopsy in all subjects. Electronic health records were used to identify those with pre-mortem echocardiography data. The extent of myocardial fibrosis at autopsy was char

SUBMITTER: Silvola H 

PROVIDER: S-EPMC12703369 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature