Thyroid Volume Measurement With AI-Assisted Freehand 3D Ultrasound Compared to 2D Ultrasound-A Clinical Trial.

ABSTRACT:

Background

Accurate thyroid volume assessment is critical in thyroid disease diagnostics, yet conventional high-resolution 2D ultrasound has limitations. Freehand 3D ultrasound with AI-assisted segmentation presents a potential advancement, but its clinical accuracy requires validation.

Method

This prospective clinical trial included 14 patients scheduled for total thyroidectomy. Preoperative thyroid volume was measured using both 2D ultrasound (ellipsoid method) and freehand 3D ultrasound with AI segmentation. Postoperative thyroid volume, determined via the water displacement method, served as the reference standard.

Results

The median postoperative thyroid volume was 14.8 mL (IQR 8.8-20.2). The median volume difference was 1.7 mL (IQR 1.2-3.3) for 3D ultrasound and

SUBMITTER: Rask KB 

PROVIDER: S-EPMC12703570 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature