Tablet-based Cognitive Assessment Tool (TabCAT) in a multisite study of early-onset Alzheimer's disease.

ABSTRACT:

Introduction

Brief digital cognitive measures may be a valuable and scalable alternative to traditional tests for improving early detection and disease monitoring in patients with early-onset Alzheimer's disease (EOAD).

Methods

We examined the convergent, diagnostic, and neuroanatomical validity of Tablet-based Cognitive Assessment Tool (TabCAT) tests in the multisite Longitudinal Early-Onset Alzheimer's Disease Study. Four hundred seventy-five participants from 16 sites (83 cognitively unimpaired participants, 146 individuals diagnosed with mild cognitive impairment [MCI], and 246 with mild dementia) underwent TabCAT testing, including two executive/attentional tasks (Match and Flanker) and two visuospatial tasks (Line Length and Line Orientation).

Results

TabCAT tes

SUBMITTER: Njamnshi WY 

PROVIDER: S-EPMC12703652 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature