Cloud point extraction of pyridine <i>N</i>-oxides using mixed micelles of PEGylated calix[4]pyrroles and non-ionic surfactants.

ABSTRACT: Pyridine N-oxides occur in pharmaceuticals and agrochemicals as solubilizing groups or as products of the oxidative metabolism of pyridine derivatives. Aryl-extended calix[4]pyrroles are supramolecular hosts that selectively bind pyridine N-oxides in host-guest complexes. A micelle-mediated extraction method was developed for the selective extraction of pyridine N-oxides from aqueous solutions using mixed micelles composed of aryl-extended calix[4]pyrroles and the non-ionic surfactants Triton X-100 and Tergitol 15-S-7. To this end, aryl-extended calix[4]pyrroles were functionalized with three different methoxy polyethylene glycol chains, and their binding constants for pyridine N-oxide and p-phenylpyridine N-oxide were determined with NMR titration

SUBMITTER: Naulapaa J 

PROVIDER: S-EPMC12703696 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature