Effects of Quercetin on Metabolic Dysfunction-Associated Steatotic Liver Disease: A Systematic Review and Meta-Analysis.

ABSTRACT: This systematic review and meta-analysis aimed to evaluate the effects of quercetin (QE) on liver function, lipid profiles, kidney function, anthropometric measures, hematological markers, and inflammatory markers in patients with metabolic dysfunction-associated steatotic liver disease (MASLD). PubMed, Cochrane Library, Web of Science, and Embase were searched to January 26, 2025, for randomized controlled trials (RCTs). Additional gray literature sources, trial registries, and preprint platforms were screened. Weighted mean differences (WMDs) with 95% confidence intervals were calculated. Heterogeneity was assessed using the I ² statistic, and meta-regression analyses explored the influence of quercetin dose, baseline BMI, and age. Seven RCTs (540 patients) were include

SUBMITTER: Jin D 

PROVIDER: S-EPMC12703814 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature