Impact of acquisition and reconstruction parameters on quantitative accuracy in dual-layer spectral CT: A phantom study.

ABSTRACT:

Purpose

This study aims to systematically evaluate the impact of different CT acquisition and reconstruction parameters on the accuracy of dual-layer spectral CT-based functional imaging, including effective atomic number (Z_eff) maps, relative electron density (RED) maps, and virtual monochromatic images (VMIs).

Methods

A standardized phantom equipped with various material inserts, including air, soft-tissue-equivalent, polymer, and bone-equivalent materials, was scanned using a dual-layer spectral CT system. The investigated acquisition and reconstruction parameters included tube voltage, tube current-time product (mAs), reconstruction thickness, pitch, and reconstruction filter. Quantitative accuracy was assessed for RED and Z_eff by comparison with ma

SUBMITTER: Leng L 

PROVIDER: S-EPMC12703825 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature