Synergistic potentiation of antibiotics by chamomile phytochemicals against multidrug-resistant Helicobacter pylori.

ABSTRACT:

Background

Helicobacter pylori is a significant global health issue, infecting nearly half of the population. Increasing antibiotic resistance leads to treatment failures. This study examined the antibacterial effects of chamomile ethanolic extract, both alone and combined with standard antibiotics, as a potential approach to fighting antibiotic-resistant H. pylori strains.

Methods

Thirty antral gastric biopsies were collected from patients undergoing diagnostic upper endoscopy at El-Demerdash Hospital in Cairo, Egypt. H. pylori isolates were identified by rapid urease test (RUT), cultured, and tested for antimicrobial susceptibility to clarithromycin (CLR, 15 µg), metronidazole (MET, 5 µg), amoxicillin (AX, 25 µg), tetracycline (TE, 30 µg), rifampicin (RA, 30 µg), and levof

SUBMITTER: Ali MMMM 

PROVIDER: S-EPMC12703921 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature