Cone beam computed tomography-guided online adaptive radiation therapy: Clinical implementation in breast and axillary target volumes.

ABSTRACT:

Background and purpose

Daily differences in breast contour and arm positioning can result in frequent re-positioning and offline re-planning in postoperative breast radiotherapy (RT). Online adaptive radiotherapy (oART) enables daily adaptation of the radiotherapy treatment plan. This study aimed to implement oART in breast and axillary target volumes to eliminate the need for repositioning and replanning.

Materials and methods

Patients referred for postoperative partial breast irradiation (PBI) and whole breast irradiation (WBI)/post-mastectomy radiotherapy (PMRT) with or without axillary levels I-II (5x5.2 Gy) or I-IV (15x2.67 Gy) were included. On-couch treatment times were evaluated as well as dosimetry, target volume, acute toxicity, and in-house satisfaction questionna

SUBMITTER: van Vlaenderen ARW 

PROVIDER: S-EPMC12704200 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature