Cell Behavior and Complex Mechanical Properties of 3D Printed Cell-Laden Alginate-Gelatin Macroporous Mesostructures.

ABSTRACT: Bioprinting involves additive manufacturing of materials containing living cells, known as bioinks, which are formulated from cytocompatible hydrogel precursors. The bioink's characteristics before, during, and after crosslinking are critical for its printability, structural resolution, shape fidelity, and cell viability. The mechanical properties of printed constructs can be strongly influenced by their macroporous mesostructure, including pore size, filament diameter, and layer height, and are crucial for the intended applications in tissue engineering or regenerative medicine. It is known that the mechanical properties of hydrogels influence cell performance, but in turn, cells can also alter the mechanical properties of bioprinted constructs, which remain poorly understood. To explore

SUBMITTER: Murenu N 

PROVIDER: S-EPMC12704233 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature