Plasmapheresis in Acute Hypertriglyceridemia-Induced Pancreatitis-The PHIP-JuGa-Study.

ABSTRACT:

Background and aims

The incidence of acute pancreatitis is increasing in the Western world. About 10% of cases are caused by hypertriglyceridemia. Plasmapheresis was shown to reduce serum triglyceride (TG) levels, and current apheresis guidelines recommend its use in severe acute hypertriglyceridemia-induced pancreatitis (HIP). However, data on safety and efficacy are lacking. This study aimed to evaluate the clinical efficacy of plasmapheresis in hypertriglyceridemia-induced pancreatitis.

Methods

This is a retrospective multicenter cohort study of patients hospitalized for an episode of hypertriglyceridemia-induced pancreatitis from January 1, 2012 to December 31, 2022. The predefined composite primary endpoint was in-hospital mortality and organ failure. To reduce allocati

SUBMITTER: Staudacher JJ 

PROVIDER: S-EPMC12704568 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature