Global transfusion practices in septic patients in the intensive care unit: insights from the InPUT-study sub-analysis.

ABSTRACT:

Background

Transfusion practices among intensive care unit (ICU) patients with sepsis vary widely. While restrictive hemoglobin thresholds for red blood cell (RBC) transfusion are well studied, the indications and thresholds for platelet and plasma transfusions remain uncertain.

Methods

We performed a sepsis-specific sub-analysis of the International Point Prevalence Study of Intensive Care Unit Transfusion Practices, a prospective, multicenter, observational study capturing all adult ICU admissions during four pre-scheduled weeks between March 2019 and October 2022. Patients admitted with sepsis or septic shock, or who developed sepsis during their ICU stay, were included. We recorded demographics, daily laboratory values, and transfusion triggers. Primary endpoints were th

SUBMITTER: Kurucz VC 

PROVIDER: S-EPMC12704699 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature