Epidemiology of Neuroendocrine Neoplasia Worldwide: A Review of the Literature (2012-2022).

ABSTRACT:

Background

The incidence of neuroendocrine neoplasms (NENs) has been rising globally. However, epidemiological studies on NENs often lack comprehensive geographical comparisons, with limited reporting on demographic variations, risk factors, and tumour site-specific trends.

Summary

This review examines the global epidemiological trends in NENs, focussing on incidence, demographic variations, risk factors, and survival outcomes across tumour sites. A literature search was conducted using PubMed, MEDLINE, and Embase, identifying 74 eligible epidemiology-focused studies on adult NEN populations published between 2012 and October 13, 2022. Results indicate a rising incidence of NENs across multiple sites, with significant regional and demographic variations. Gastrointestinal NEN

SUBMITTER: Nwoguh CA 

PROVIDER: S-EPMC12705086 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature