Sex Disparities in Intracranial Aneurysm Trial Participation: A Systematic Review and Meta-Analysis.

ABSTRACT:

Introduction

Females have a higher incidence of aneurysmal subarachnoid hemorrhage and a higher prevalence and rupture risk of unruptured intracranial aneurysms than men. Underrepresentation of females in clinical trials would, therefore, limit their generalizability. The study aimed to evaluate sex disparities in aneurysmal subarachnoid hemorrhage and unruptured intracranial aneurysm trial enrollment and identify factors influencing female representation.

Methods

The authors searched Ovid Medline, Embase, Cochrane Central, Clinicaltrials.gov, and International Clinical Trials Registry for clinical trials on aneurysmal subarachnoid hemorrhage or unruptur

SUBMITTER: Janssen HC 

PROVIDER: S-EPMC12705092 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature