Choroidal Metastasis of a Cutaneous Melanoma: A Case Report.

ABSTRACT:

Introduction

We report the clinical, imaging, histopathological, and genetic features of a choroidal metastasis originating from a cutaneous melanoma.

Case presentation

A 92-year-old woman presented with an asymptomatic pigmented lesion in her right eye. She had a history of prior cutaneous melanoma. Workup revealed widespread metastases to the liver, lungs, and brain. Histopathology (post-mortem eye) showed melanoma cells of the epithelioid cell type. Genetic analysis was positive for the BRAF V600K variant, confirming the cutaneous origin of the choroidal tumour.

Conclusion

Choroidal metastasis of a cutaneous melanoma is a rare manifestation that can be mistaken for a primary choroidal melanoma. A comprehensive clinical history, histopathology, and genetic analysis

SUBMITTER: Jiang J 

PROVIDER: S-EPMC12705110 | biostudies-literature | 2025 Jan-Dec

REPOSITORIES: biostudies-literature