Early Weight Loss and Other Factors Associated With Clinically Significant Weight Loss in Two Commercial Weight Loss Programmes.

ABSTRACT: This secondary analysis assessed potential factors associated with achieving ≥ 5% or ≥ 10% weight loss among adults in a clinical trial evaluating two commercial weight loss programmes. Participants [n = 124, 45.7 (13.1) years, 20.2% male, BMI 34.4 (3.4) kg/m²] were randomised to the Medifast or OPTAVIA weight loss programme, both of which included meal replacements and behavioural support. Multivariable logistic regression analyses were used to assess early weight loss thresholds (percent weight loss at 2 and 4 weeks) and potential demographic, anthropometric, behavioural, and lifestyle factors associated with ≥ 5% or ≥ 10% weight loss at 16 weeks. Age, education, ≥ 1% weight loss by Week 2, ≥ 2% weight loss by Week 4, number of support contacts and programme adherence through

SUBMITTER: Coleman CD 

PROVIDER: S-EPMC12705255 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature