Exploring the Relationship Between Obesity, Weight Loss and Health-Related Quality of Life: An Updated Systematic Review of Reviews.

ABSTRACT: The aim of this systematic literature review (SLR) of reviews was to update the evidence, established in a 2017 SLR, on the impact of obesity and weight loss by various interventions on health-related quality of life (HRQoL). In total, eight SLRs and/or meta-analyses published since 2017 were identified. The results consistently demonstrated a negative association between obesity and HRQoL, with some evidence suggesting poorer HRQoL in people with adverse metabolic profiles. In addition to substantial weight or body mass index reduction, metabolic and bariatric surgery (MBS) or endoscopic bariatric therapies resulted in significant and clinically relevant HRQoL improvements, with pronounced and persistent effects on the physical components in particular. HRQoL typically improved within 1-2

SUBMITTER: Flolo TN 

PROVIDER: S-EPMC12705258 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature