A prognostic model based on gamma-glutamyl transpeptidase-derived neutrophil-platelet for predicting intrahepatic recurrence in hepatocellular carcinoma.

ABSTRACT:

Aims

This study aims to investigate the prognostic significance of the combined GNR and GPR in patients with early-stage hepatitis B virus-associated hepatocellular carcinoma (HBV-HCC).

Methods

Retrospective analysis was performed on clinical data of 145 HBV-infected patients with early-stage HCC (ESHCC) who underwent radiofrequency ablation (RFA) and/or surgical resection. Patients were randomly allocated to training (n = 103) and validation (n = 42) cohorts for further survival analysis and model verification. The area under the receiver operating characteristic curves (ROC) was used for evaluating the diagnostic performance of ERM-model. And at the optimal cutoff, a survival analysis on all patients was conducted. Simultaneously, all patients were divided into different s

SUBMITTER: Huo Z 

PROVIDER: S-EPMC12705514 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature