Outcomes of Air Versus Saline-filled Breast Expanders: A Systematic Review and Meta-analysis.

ABSTRACT:

Background

Among the possible implant-based reconstructive strategies, the two-stage tissue expander-to-implant procedure is one of the most common options in patients not ideal candidate to direct-to-implant reconstruction. Recently, other filling options such as air or carbon dioxide (CO2) have been reported as alternative fill media than saline for tissue expansion. The aim of this systematic review was to qualitatively and quantitatively synthetize the available evidence on the topic.

Methods

A systematic review and meta-analysis were conducted, and they were reported according to PRISMA guidelines. PubMed, Embase, and Cochrane Library databases were accessed. Only studies with a control group were included. Risk ratios for complications were assessed between breast tiss

SUBMITTER: Alessandri Bonetti M 

PROVIDER: S-EPMC12705835 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature