Impact of dynapenia, presarcopenia and sarcopenia in chronic obstructive pulmonary disease: a prospective cohort study.

ABSTRACT:

Background

Reduced muscle strength and decreased muscle mass (sarcopenia) are known predictors of poor prognosis in chronic obstructive pulmonary disease (COPD). Isolated muscle weakness (dynapenia) or low muscle mass alone (presarcopenia) may also negatively impact outcomes. This study aims to compare the prognostic significance of dynapenia, presarcopenia and sarcopenia.

Methods

This prospective study enrolled patients with spirometry-confirmed COPD at a tertiary medical centre. Participants were categorised into dynapenia, presarcopenia and sarcopenia based on the presence of reduced handgrip strength (<28 kg for men, <18 kg for women) and/or decreased muscle mass (<7.0 kg/m² for men, <5.7 kg/m² for women). Physical performance was assessed using a 6

SUBMITTER: Chen SY 

PROVIDER: S-EPMC12706201 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature