Optimising time-limited trials in acute respiratory failure: a multicentre focused ethnography protocol.

ABSTRACT:

Introduction

The 'time-limited trial' for patients with critical illness is a collaborative plan made by clinicians, patients and families to use life-sustaining therapies for a defined duration. After this period, the patient's response to therapy informs decisions about continuing recovery-focused care or transitioning to comfort-focused care. The promise of time-limited trials to help navigate the uncertain limits and benefits of life-sustaining therapies has been extensively discussed in the palliative and critical care literature, leading to their dissemination into clinical practice. However, we have little evidence to guide clinicians in how to conduct time-limited trials, leading to substantial variation in how and why they are currently used. The overall purpose of this st

SUBMITTER: Kruser JM 

PROVIDER: S-EPMC12706242 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature