Association between carotid-femoral pulse wave velocity and cardiovascular disease in individuals with moderate blood pressure: a systematic review and individual participant meta-analysis.

ABSTRACT:

Objectives

The predictive value of carotid-femoral pulse wave velocity (cfPWV) for cardiovascular (CV) events in individuals with blood pressure (BP) 120-159/80-99 mm Hg, where more accurate risk stratification has the greatest clinical effect, is unknown. This study aims to determine whether cfPWV improves the prediction of CV events beyond traditional risk factors in individuals with moderate BP.

Design

A systematic review and meta-analysis.

Data sources

PubMed and EMBASE were searched through April 2023.

Eligibility criteria

We included prospective, population-based cohort studies with ≥1 year follow-up that directly measured cfPWV as an index of arterial stiffness and reported incident CV disease (CVD), atherosclerotic CVD (ASCVD), coronary heart disease, s

SUBMITTER: Pavey H 

PROVIDER: S-EPMC12706244 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature