Genetic and Environmental Risk Factors for Intermittent Explosive Disorder, ADHD and Conduct Disorder: Shared and Unique Influences.

ABSTRACT:

Objective

This systematic review examines the shared and unique risk factors for intermittent explosive disorder (IED), attention-deficit/hyperactivity disorder (ADHD) and conduct disorder (CD), aiming to provide a comprehensive understanding of their etiological pathways and inform future intervention strategies.

Methods

We conducted a comprehensive search across seven databases (Web of Science, APA PsycINFO, MEDLINE, PubMed, Cochrane, CENTRAL and Embase) for studies examining risk factors for IED, ADHD and CD. A total of 44 studies were included, focusing on genetic, environmental and psychosocial factors. We employed the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) guidelines for study selection and quality assessment.

Results

Forty-fo

SUBMITTER: Liu F 

PROVIDER: S-EPMC12706422 | biostudies-literature | 2025 Nov-Dec

REPOSITORIES: biostudies-literature