Functional capacity in Peruvian people with Alzheimer's disease and frontotemporal dementia.

ABSTRACT:

Introduction

Functional impairment across degenerative dementias remains understudied in Latin American contexts. We aimed to assess total and item-level functional performance, determine specific instrumental activities, and identify differences in functional profiles between groups.

Methods

In this cross-sectional study, 1445 participants were classified according to the Pfeffer Functional Activities Questionnaire (PFAQ). Statistical comparisons were adjusted for age, sex, and education using linear regression residuals and corrected for multiple comparisons.

Results

Functional impairment increased progressively from normal cognition to dementia. Alzheimer's disease (AD) and frontotemporal dementia (FTD) groups showed significantly greater total PFAQ scores compared

SUBMITTER: Custodio N 

PROVIDER: S-EPMC12706628 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature