Tumor Habitats Based on Multiparametric MRI Distinguish Atypical Glioblastoma From Primary Central Nervous System Lymphoma: Imaging-Pathologic Correlation.

ABSTRACT:

Background

Atypical glioblastoma (GBM) (minimal or no necrosis on MRI) and primary central nervous system lymphoma (PCNSL) are difficult to distinguish on MRI; whether tumor habitat can more accurately distinguish atypical GBM from PCNSL remains uncertain.

Purpose

To evaluate the diagnostic performance with tumor habitats, apparent diffusion coefficient (ADC), and edema index (EI) to distinguish atypical GBM from PCNSL.

Study type

Retrospective.

Population

One hundred twenty-five patients (63 male and 62 female) diagnosed with atypical GBM or PCNSL were included.

Field strength/sequence

1.5 T and 3.0 T, Axial ADC and T1 contrast-enhanced spin-echo inversion recovery sequence (T1-CE).

Assessment

The tumor habitat was derived using T1-CE and ADC seq

SUBMITTER: Sun MN 

PROVIDER: S-EPMC12706713 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature