Unveiling hepatitis E virus diversity in Sudan's internally displaced populations: a molecular epidemiology approach.

ABSTRACT:

Background

Hepatitis E virus (HEV) is recognized as a cause of acute viral hepatitis, particularly in low-resource and humanitarian settings, although its burden varies across different populations and geographic areas. Internally displaced persons (IDPs) are at high risk due to inadequate sanitation and contaminated water. This study aimed to characterize the molecular epidemiology and genotypes of HEV among IDPs in Al-Azaza Camp, Blue Nile State, Sudan.

Methods

A cross-sectional study was conducted from August to December 2021 during the rainy season. Serum samples from 1,078 participants were screened for anti-HEV IgM and IgG antibodies. A subset of 20 IgM-positive samples was selected for molecular analysis using real-time RT-PCR. Eighteen high-quality RNA-positive sampl

SUBMITTER: Osman HA 

PROVIDER: S-EPMC12706927 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature