Patient-reported outcomes during pregnancy and delivery in epidermolysis bullosa.

ABSTRACT:

Background

Research on pregnancy in women with epidermolysis bullosa (EB) and its effect on maternal disease activity is limited. Lack of evidence poses significant challenges for patient management.

Objective

This study aimed to retrospectively characterise the spectrum and course of patient-reported symptoms and complications during pregnancy referring to the EB House Austria patient cohort.

Methods

Data on pregnancy outcomes, clinical symptoms, and EB disease activity before, during, and after pregnancy were collected using a structured questionnaire. To specify the impact of disease severity, the responders were classified into three groups based on the individual overall EB phenotype (mild, moderate, severe) prior to pregnancy (baseline). The pseudonymised data w

SUBMITTER: Zott A 

PROVIDER: S-EPMC12706982 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature