Antimicrobial resistance is widespread among intestinal and extra-intestinal <i>Bacteroides fragilis</i> strains.

ABSTRACT: Bacteroides fragilis is an important member of the human gut microbiota, where it contributes to immune modulation, intestinal barrier integrity, and colonization resistance. Despite its beneficial roles as a symbiont in the gut, B. fragilis is also the most commonly isolated anaerobe in clinical infections, implicated in intra-abdominal abscesses, bloodstream infections, and soft tissue infections. Antimicrobial resistance (AMR) is increasingly recognized as a major factor in its transition from symbiont to opportunist; however, the relationship between resistance and anatomical site of isolation remains poorly defined. Here, we compared AMR phenotypes and genotypes between intestinal and extra-intestinal B. fragilis isolates to assess whether clinical strains are enr

SUBMITTER: Carrillo Terrazas M 

PROVIDER: S-EPMC12707147 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature