Minimally Invasive Subretinal Perfluorocarbon Liquid (PFCL) Removal.

ABSTRACT:

Purpose

Perfluorocarbon liquid (PFCL) is widely used in retinal surgery; however, it can be complicated by subretinal retention that can affect/threaten fovea. A number of different approaches have been explored to remove retained PFCL. Here, we investigate the use of microneedles with internal diameters as small as 49 G.

Methods

An in vitro model was used to examine the rate of aspiration of a fixed volume of 250 µL PFCL, whereby 30, 41, 43, and 49 gauge needles were examined. An ex vivo porcine model was then used to confirm whether subretinal PFCL could be consistently aspirated without blockage. Finally, this technique was used during pars plana vitrectomy (PPV) in 10 patients presenting with subfoveal or parafoveal retained PFCL.

Results

Mean aspiration of 250 µL

SUBMITTER: Ching J 

PROVIDER: S-EPMC12707325 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature