Free Fatty Acids and Complex Lipids in Patients With Severe Obesity Treated With Roux-En-Y Gastric Bypass: Impact of Diabetes Status.

ABSTRACT: This study investigates the relationship between eight free fatty acids (FFA), triglycerides (TAG), and phosphatidylcholines (PC) after Roux-en-Y gastric bypass (RYGB) to obtain insight into changes in lipid metabolism that might be causally related to postsurgery Type 2 diabetes remission. We measured the FFA, TAG, and PC before and up to 2 years after RYGB in three patient groups: one nondiabetes group (n = 149), one diabetes group with postoperative remission (n = 33), and one diabetes group with persistent diabetes after surgery (n = 20). Pre- and postoperative Pearson's correlations and linear regression models were used to assess the relationship between concentrations of individual FFA, TAG, and PC. At all timepoints, FFA explained more of the variance in PC tha

SUBMITTER: Eriksen F 

PROVIDER: S-EPMC12707549 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature